Sabari BR (2020). Biomolecular condensates and gene activation in development and disease. Developmental Cell. in press. scheduled October 12, 2020. Download

Sabari BR, Dall’Agnese A, Young RA (2020). Biomolecular condensates in the nucleus. Trends in Biochemical Sciences. Online ahead of print.

Klein IA*, Boija A*, Afeyan LK, Hawken SW, Fan M, Dall’Agnese A, Oksuz O, Henninger JE, Shrinivas K, Sabari BR, et al. (2020). Partitioning of cancer therapeutics in nuclear condensates. Science 368, 1386-1392

Zamudio A.V., Dall'Agnese A, Henninger JE, Manteiga JC, Afeyan LK, Hannett NM, Coffey, EL, Li CH, Oksuz O, Sabari BR, et al. (2019). Mediator Condensates Localize Signaling Factors to Key Cell Identity Genes. Molecular Cell 76, 1-14.
 

Guo YE*, Manteiga JC*, Henninger JE, Sabari BR, Dall'Agnese A, et al. (2019). Pol II phosphorylation regulates a switch between transcriptional and splicing condensates. Nature 13, 1–6.

 

Shrinivas K*, Sabari BR*, Coffey EL, Klein IA, Boija A, Zamudio AV, Schuijers J, Hannett NM, Sharp PA, Young RA, Chakraborty A (2019). Enhancer Features that Drive Formation of Transcriptional Condensates. Molecular Cell 75, 549–561.
 

Boija A*, Klein IA*, Sabari BR, Dall’Agnese A, et al. (2018) Transcription factors activate genes through the phase separation capacity of their activation domains. Cell 176, 1842-1855.
 

Sabari BR*, Dall'Agnese A*, Boija A, Klein IA, et al. (2018) Coactivator condensation at super-enhancers links phase separation and gene control. Science 361 

 

Sabari BR*, Zhang D*, Allis CD, Zhao Y. (2017) Metabolic regulation of gene expression through histone acylations. Nature Reviews Molecular Cell Biology 18, 90–101 

 

Melo FR, Wallerman O, Paivandy A, Calounova G, Gustafson A-M, Sabari BR, Zabucchi G, Allis CD, Pejler G. (2017) Tryptase-catalyzed core histone truncation: a novel epigenetic regulatory mechanism in mast cells. J. Allergy Clin. Immunol 140, 474–485.

 

Bayliss J, Mukherjee P, Lu C, Jain SU, Chung C, Martinez D, Sabari BR, et al. (2016) Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas. Science Translational Medicine 23

 

Li Y*, Sabari BR*, Panchenko T*, Wen H, Zhao D, Guan H, Wan L, Huang H, Tang Z, Zhao Y, Roeder RG, Shi X, Allis CD, Li H. (2016) Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain. Molecular Cell 62, 181–93. 

 

Sabari BR, Tang Z, Huang H, Yong-Gonzalez V, Molina H, Kong HE, Dai L, Shimada M, Cross JR, Zhao Y, Roeder RG, Allis CD. (2015) Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation. Molecular Cell 58, 203–15. 

 

Huang H, Sabari BR, Garcia BA, Allis CD, Zhao Y. (2014) SnapShot: Histone Modifications. Cell 159

 

Dai L, Peng C, Montellier E, Lu Z, Chen Y, Ishii H, Debernardi A, Buchou T, Rousseaux S, Jin F, Sabari BR, Deng Z, Allis CD, Ren B, Khochbin S, Zhao Y. (2014) Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark. Nature Chemical Biology 10, 365–370. 

Contact

UT Southwestern Medical Center

Cecil H. and Ida Green Center
for Reproductive Biology Science

J7.130

5323 Harry Hines Blvd

Dallas, TX 75390

  • Twitter - White Circle

© 2020 by Ben Sabari

This website reflects only the views of the author and is not a publication of UT Southwestern, which bears no responsibility for its content.